£21.99 – £54.99
Citicoline is a nutritional supplement popular for enhancing cognition. It’s especially popular for protecting the brain from age-related cognitive decline or other forms of memory impairment.
Suitable for: Vegetarians, Vegans, Allergen Free, Dairy Free, Gluten Free, Contains No Artificial Colours or Flavourings.
Citicoline is a nutritional supplement popular for enhancing cognition. It’s especially popular for protecting the brain from age-related cognitive decline or other forms of memory impairment. Our body naturally creates citicoline as an intermediary in the production of phospholipids — which themselves are a key component of cell membranes, especially in the brain.
You can find citicoline in capsulated form, usually in combination with other nootropics.
Citicoline is a nutritional prodrug — meaning that it’s converted in the body into the active constituents. In its raw form, citicoline doesn’t have much effect on the body. It needs to first be processed by the liver — where it’s converted into choline and cytidine (and later uridine).
1. Choline
Choline is used to manufacture neurotransmitters in the brain like acetylcholine. This neurotransmitter is critically important in the process of learning and memory, as well as muscle movement.
A lot of nootropics are designed to work through the effects of this neurotransmitter — such as the nootropic powerhouses piracetam and aniracetam.
By providing the raw materials to manufacture acetylcholine, CDP Choline can help optimise for both learning and memory.
2. Cytidine/Uridine
Cytidine may be used as is — or later converted to uridine.
Both cytidine and uridine are nucleotides that make up nucleic acid in our RNA.
RNA is required for all cellular processes. The information stored in the DNA is transferred to RNA where it’s then converted into proteins and other compounds manufactured by the cell.
Uridine is especially important for brain health because it’s involved with the P2Y2 receptors — which is involved with nerve growth factor (NGF). Together NGF and the P2Y2 receptor regulate the regeneration of nerve cells in the brain.
This process is commonly referred to as neuroplasticity — the ability for the brain to change and repair itself once it becomes damaged.
The cause of damage could be traumatic injury — but more commonly the cause is internal.
Buildups of misshapen proteins like amyloid beta or TAU proteins can lead to a gradual shrinkage in the grey matter of the brain.
This grey matter is where most of our higher thought takes place.
Without high density, in our grey matter we begin to lose our edge. Everything from memory to decision making can start to suffer.
Other Effects of Citicoline
Citicoline has an incredibly diverse set of benefits to offer the brain.
On top of providing nutritional support for the manufacture of nerve cells, neurotransmitters, and RNA, it also interacts with the hypothalamus — the region in the brain responsible for controlling the stress response.
People are using the compound to improve the brains ability to resist the negative effects of stress — this is the same mechanism of action for adaptogens like Rhodiola or Ashwagandha.
Citicoline has many uses — it provides protection from age-related loss of grey matter in the brain, supports the stress response system in the hypothalamus, provides nutritional support for the RNA and neurotransmitters, and is involved with glucose metabolism in the brain.
Most people take the compound for its neuroprotective effects long-term. However, others prefer to use the supplement to promote memory and concentration and to prime the brain for upcoming periods of emotional and physical stress.
| Amount Per Serving (1 Capsule): Citicoline (250mg). Ingredients: Citicoline (250mg), Rice Bran, Magnesium Stearate, Vegetarian Capsule (Hypromellose). |
| Recommended Dose Take 1 capsule (200mg) daily with a meal, or as advised by your healthcare professional. |
| Ingredients: Citicoline Pure Powder. |
| Recommended Dose Mix 300mg (1/2 scoop) into 200ml of liquid and consume 2 times a day with a meal, or as advised by your healthcare professional. |
ITThanks all perfect
Hi there, We're so glad to hear it! Thank you for leaving this review. Thanks, The Focus Supplements Team
PortugalI have been waiting for a month now. Plus I had to pay 20€ more of customs. I know Brexit happened, but why do you claim to deliver in 1-3 weeks and shipping costs? At least some info that this could be subject to customs duties. Unless you have a seller within the EU, this is the last time I buy from you.
Hi José, I'm very sorry to hear that this was your experience ordering with us. I hope you have by now received your order but please let me know if not! Our customers should not be charged custom fees, and if they do we advise them to get in touch with us. Unfortunately we are finding that orders are taking longer than usual to reach our customers, so we are working on a way to improve this. With regards to working within the EU, watch this space! Thanks, The Focus Supplements Team
GBExcellent! It’s very helpful for me and definitely I will buy again. Thanks
Hi there, Thank you for taking the time to leave us a review, we really appreciate it! We're so pleased that you are happy with our Citicoline. Thanks, The Focus Supplements Team
ITI definitely recommend FS as a reliable Supplement supplier. The quality of their products is awesome. My only concern, as I’m not in the UK, is that I hope not having trouble with deliveries in EU in the near future due to Brexit.. I want to go on purchasing supplements (e.g. Citicoline..) from this company
Hi Mark, Thank you so much for your kind words, we really appreciate the recommendation. We are finding that deliveries are taking longer than usual at the moment, but we are working on improving this. With regards to selling within the EU, watch this space! Thanks, The Focus Supplements Team
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